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EC Number
Activating Compound
Commentary
Reference
3.1.26.3
ATP
ATP hydrolysis is required for Dicer-2 to process long dsRNA, but not pre-miRNA
716223
3.1.26.3
dsRNA
activates Dicer-2
716223
3.1.26.3
EDTA
less than 1 mM
134349
3.1.26.3
glutamate
extends salt concentration range
134358
3.1.26.3
lamB RNA
MicA cleavage by RNase III is facilitated by base pairing with MicA mRNA target(s)
716386
3.1.26.3
Loquacious-PB
activates dsRNA cleavage of Dicer-2
716223
3.1.26.3
more
enzyme activity is increased at low osmolarity
730935
3.1.26.3
more
silencing of the drosha cofactor, pasha, leads to developmental complications and consequent lethality
708793
3.1.26.3
more
T7-induced catalytic enhancement of the enzyme
731020
3.1.26.3
NH4+
-
134343
,
134364
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