EC Number |
Activating Compound |
Reference |
---|
7.1.1.9 | (3Z)-3-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-1-[3-[(5-hydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy]propyl]-1,3-dihydro-2H-indol-2-one |
compound developed for clipping cyanide from the enzyme and restoring its normal function. The binding constant with CN- is 230000 per M and its ED50 for restoring the cyanide bound CcOX activity in 10 min is 16 microM. The compound interacts with CN- over the pH range 5-10 |
752934 |
7.1.1.9 | (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate |
- |
741883 |
7.1.1.9 | 3-Amino-1,2,4-triazole |
- |
694694 |
7.1.1.9 | ADP |
- |
711289 |
7.1.1.9 | arachidonic acid |
- |
741883 |
7.1.1.9 | asolectin |
- |
396076 |
7.1.1.9 | asolectin |
20-30% more activity in the presence of asolectin |
396089 |
7.1.1.9 | Caffeine |
increases Cox7c mRNA expression in PC-12 cells. This occurrs at the level of transcription and is mediated by a segment of the Cox7c promoter |
694263 |
7.1.1.9 | Caffeine |
increases Cox7c mRNA expression in the male striatum. Cox7c is up-regulated in the striatum of male but not female mice after receiving a single dose of caffeine. Cox1 and Cox4 are also stimulated by caffeine in a male-specific fashion. A2AR-specific agonist 2-[p-(2-carboxyethyl)phenethylamino]-5'-N-ethylcarboxamidoadenosine counteracts the elevation of Cox expression and activity by caffeine |
694263 |
7.1.1.9 | cardiolipin |
- |
395996, 396045, 396069 |