EC Number   |
Inhibitors   |
Structure   |
---|
1.1.5.12 | cyanide |
stimulates D-lactate dehydrogenase activity at neutral pH, though it inhibits the activity at alkaline pH. At 1.5 mM, 50% inhibition at pH 9.3 |
   |
1.1.5.12 | EDTA |
partial inhibition |
   |
1.1.5.12 | EDTA |
5 mM, partial inhibition; 5 mM, partial inhibition of activity |
   |
1.1.5.12 | Fe2+ |
complete inhibition |
   |
1.1.5.12 | Fe2+ |
5 mM, complete inhibition; 5 mM, complete inhibition of activity |
   |
1.1.5.12 | Mg2+ |
5 mM, partial inhibition; 5 mM, partial inhibition of activity |
   |
1.1.5.12 | Mn2+ |
complete inhibition |
   |
1.1.5.12 | Mn2+ |
5 mM, complete inhibition; 5 mM, complete inhibition of activity |
   |
1.1.5.12 | more |
not inhibited by 4-chloromercuribenzoate, N-ethylmaleimide, or 5,5'-dithiobis(2-nitrobenzoic acid) |
 |
1.1.5.12 | NaN3 |
inhibits electron transfer from cytochrome c to molecular oxygen |
   |