EC Number |
Inhibitors |
Structure |
---|
1.14.11.21 | 4'-ethynyl proclavaminate |
noncompetitive |
|
1.14.11.21 | 4'-vinyl proclavaminate |
noncompetitive |
|
1.14.11.21 | 4-cyclopropyl proclavaminate |
noncompetitive |
|
1.14.11.21 | ascorbate |
inactivation due to release of peroxide from reaction of ascorbate and O2 in absence of proclavaminate, but in presence of Fe2+, t1/2: 50 min, catalase protects |
|
1.14.11.21 | Co2+ |
complete inhibition competitive to Fe2+, but stabilizes the enzyme against self-inactivation in absence of proclavaminate |
|
1.14.11.21 | Co2+ |
competitive |
|
1.14.11.21 | diethyl dicarbonate |
isozyme CS2, rapid inactivation at pH 6.0, 25°C, t1/2: 1.1 min |
|
1.14.11.21 | N-bromoacetyl-L-arginine |
isozyme CS2, inactivation, at 7.5 mM half-life of 11.2 min at 30°C, Co2+ competes, substrates protect |
|
1.14.11.21 | N-ethylmaleimide |
inactivation |
|