EC Number |
Inhibitors |
Structure |
---|
1.1.1.214 | (R)-pantolactone |
substrate inhibition of the recombinant isozyme expressed in Escherichia coli at a concentration above 10 mg/ml |
|
1.1.1.214 | 2-keto-4-hydroxybutyrolactone |
strong and uncompetitive inhibitor |
|
1.1.1.214 | Ag+ |
1 mM, complete inhibition |
|
1.1.1.214 | Co2+ |
1 mM, 81.9% residual activity |
|
1.1.1.214 | Cu2+ |
1 mM, 67.8% residual activity |
|
1.1.1.214 | EDTA |
1 mM, 72.9% residual activity |
|
1.1.1.214 | Fe2+ |
1 mM, 81% residual activity |
|
1.1.1.214 | Mg2+ |
1 mM, 67.6% residual activity; 1 mM, 80.2% residual activity |
|
1.1.1.214 | more |
not inhibitory: 1 mM Ni2+ or Ca2+ |
|
1.1.1.214 | Pb2+ |
1 mM, complete inhibition |
|