EC Number |
Inhibitors |
Structure |
---|
1.1.1.312 | 2-pyrone-4,6-dicarboxylic acid |
non-competitive inhibition with respect to 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde |
|
1.1.1.312 | 5,5'-dithiobis(2-nitrobenzoate) |
1 h at 0.1 mM inhibits 98% of enzyme activity |
|
1.1.1.312 | Blue dextran |
competitive inhibitor with respect to NADP+ |
|
1.1.1.312 | HgCl2 |
- |
|
1.1.1.312 | HgCl2 |
1 h at 0.01 mM inhibits 83% of enzyme activity |
|
1.1.1.312 | methoxy Reactive Blue 2 |
inhibits the enzyme non-competitively with respect to 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde and competitively with respect to NADP+ |
|
1.1.1.312 | Monoiodoacetic acid |
weaker inhibitor than p-chloromercuribenzoate or HgCl2 |
|
1.1.1.312 | more |
not: various metal ions, metal chelating reagents, reducing reagents |
|
1.1.1.312 | N-ethylmaleimide |
weaker inhibitor than p-chloromercuribenzoate or HgCl2 |
|
1.1.1.312 | NADH |
competitive inhibition with respect to NAD+, non-competitive inhibition with respect to 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde |
|