EC Number   |
Inhibitors |
Structure |
|---|
   1.14.11.67 | (3-phenyl-1-(p-tolyl)-1H-pyrazol-4-yl)(4-(2-(pyrrolidin-1-yl) ethyl)piperazin-1-yl) methanone |
- |
 |
| 1.14.11.67 | (E)-2-((3-(4-(dimethylamino)but-2-enamido)-phenyl)(2-(piperidin-1-yl)ethoxy)methyl)thieno[3,2-b]pyridine-7-carboxylic acid |
- |
  |
| 1.14.11.67 | (R)-2-(1-(1-benzoylpiperidin-3-yl)-1H-1,2,3-triazol-4-yl)isonicotinic acid |
- |
|
| 1.14.11.67 | 1-(2-methoxyphenyl)-N-(2-methyl-2-morpholinopropyl)-3-phenyl-1H-pyrazole-4-carboxamide |
- |
|
| 1.14.11.67 | 1-(3-(ethylsulfonyl)phenyl)-2-(4-(pyridin-2-yl)thiazol-2-yl)ethan-1-one |
- |
|
| 1.14.11.67 | 1-(3-(methylsulfonyl)phenyl)-2-(4-(pyridin-2-yl)thiazol-2-yl)ethan-1-one |
- |
|
| 1.14.11.67 | 1-(4-(methylsulfonyl)phenyl)-2-(4-(pyridin-2-yl)thiazol-2-yl)ethan-1-one |
- |
|
| 1.14.11.67 | 1-(4-methoxyphenyl)-N-(2-methyl-2-morpholinopropyl)-3-phenyl-1H-pyrazole-4-carboxamide |
compound is a cellular active KDM5B inhibitor that can inhibit MKN45 cell proliferation, wound healing and migration. The compound can bind and stabilize KDM5B and induce the accumulation of H3K4me2/3 |
|
| 1.14.11.67 | 1-phenyl-2-(4-(pyridin-2-yl)thiazol-2-yl)ethan-1-one |
- |
|
| 1.14.11.67 | 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)-N-ethylisonicotinamide |
- |
|
