EC Number   |
Inhibitors |
Structure |
|---|
    1.14.13.59 | Carbonylcyanide-m-chlorophenylhydrazone |
- |
   |
| 1.14.13.59 | Carbonylcyanide-p-fluoromethoxyphenylhydrazone |
- |
|
| 1.14.13.59 | Cinnamylidene |
- |
|
| 1.14.13.59 | Cl- |
above 600 mM, enzyme exists in a reversible inactive conformation |
|
| 1.14.13.59 | FAD |
inhibition of the wild-type and mutant P14G enzymes at very high concentrations |
|
| 1.14.13.59 | FAD analogs |
complete loss of activity after prolonged incubation with 8-chloro-FAD, 8-fluoro-FAD, 8-mercapto-FAD or 8-methoxy-FAD |
|
| 1.14.13.59 | L-lysine |
substrate inhibition of the wild-type and mutant P14G enzymes |
|
| 1.14.13.59 | more |
number of cysteine residues in wild-type and mutant enzymes accessible for modification with DTNB, overview |
|
| 1.14.13.59 | more |
enzyme is sensitive to deleterious action of endoproteases trypsin, carboxypeptidase Y, and chymotrypsin, FAD and ADP protect, proteolysis of a C-terminal segment results in loss of enzyme activity |
|
| 1.14.13.59 | p-chloromercuribenzoate |
0.01 mM, 62% inhibition, reversed by dithiothreitol |
|
