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Results 1 - 8 of 8
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EC Number Inhibitors Commentary Structure
Show all pathways known for 1.5.1.39Display the reaction diagram Show all sequences 1.5.1.39AMP competitive inhibition against NADH and uncompetitive inhibition against FMN Go to the Ligand Summary Page
Show all pathways known for 1.5.1.39Display the reaction diagram Show all sequences 1.5.1.39Co2+ slight inhibition Go to the Ligand Summary Page
Show all pathways known for 1.5.1.39Display the reaction diagram Show all sequences 1.5.1.39Fe3+ slight inhibition Go to the Ligand Summary Page
Show all pathways known for 1.5.1.39Display the reaction diagram Show all sequences 1.5.1.39lumichrome 7,8-dimethylalloxazine, competitive inhibitor versus FMN, and mixed noncompetitive inhibitor with respect to NADH Go to the Ligand Summary Page
Show all pathways known for 1.5.1.39Display the reaction diagram Show all sequences 1.5.1.39Mg2+ slight inhibition Go to the Ligand Summary Page
Show all pathways known for 1.5.1.39Display the reaction diagram Show all sequences 1.5.1.39more the substrate binding order is investigated by carrying out dead-end inhibition studies using lumichrome (7,8-dimethylalloxazine) and AMP as inhibitory analogues of FMN and NADH. Strains Pd9233 and Pd9311 contain aa3-type or cbb3-type cytochrome c oxidase, respectively, as the only terminal oxidase of the respiratory electron transfer chain, the flux capacity through terminal oxidase is reduced in strain Pd9311 compared to strain Pd9233 or wild-type strain, manifested by the much lower specific activity of TMPD oxidase found in the cytoplasmic membrane fraction. The pden_5119 transcript in Pd9311 cells but not in Pd9233 cells is elevated similarly as observed in the wild-type strain growing in the presence of electron transfer inhibitors. Downregulation of terminal oxidase thus indeed results in a similar outcome as chemical inhibition Go to the Ligand Summary Page
Show all pathways known for 1.5.1.39Display the reaction diagram Show all sequences 1.5.1.39Triton X-10 slight inhibition Go to the Ligand Summary Page
Show all pathways known for 1.5.1.39Display the reaction diagram Show all sequences 1.5.1.39Tween 80 slight inhibition Go to the Ligand Summary Page
Results 1 - 8 of 8
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