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EC Number
Inhibitors
Commentary
Structure
2.3.1.225
2-bromo-palmitate
protein palmitoylation inhibitor in vivo
2.3.1.225
2-Bromopalmitate
-
2.3.1.225
2-Bromopalmitate
specific inhibitor for protein palmitoylation. Treatment compromises root hair elongation and polarity; specific inhibitor for protein palmitoylation. Treatment compromises root hair elongation and polarity
2.3.1.225
acyl-CoA binding protein
i.e. ACBP strongly suppress non-enzymatic thioacylation of cysteinyl containing peptides by long-chain acyl-CoAs, usage of purified rat and recombinant bovine liver ACBP. ACBP only modestly inhibits enzymatic thioacylation of a myristoylated peptide or G-protein K-subunits under conditions where non-enzymatic thioacylation is reduced to background
2.3.1.225
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depletion of cellular cholesterol with the drug methyl-beta-cyclodextrin results in inhibition of palmitoyltransferase activity and a redistribution of the remaining activity to membranes of higher density, the process is reversible by cholesterol addition
2.3.1.225
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acyl-CoAs of 14 carbons and longer inhibit palmitoyl-CoA labeling of both substrate and enzyme
2.3.1.225
myristoyl-CoA
-
2.3.1.225
stearoyl-CoA
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