EC Number |
Inhibitors |
Structure |
---|
2.7.4.22 | 1-[([5-oxo-4-[(2R)-tetrahydrofuran-2-ylmethyl]-4,5-dihydro-1H-1,2,4-triazol-3-yl]sulfanyl)acetyl]piperidine-4-carboxylic acid |
- |
|
2.7.4.22 | 1-[2-[(2-amino-6-phenylpyrimidin-4-yl)amino]phenyl]ethanone |
- |
|
2.7.4.22 | 2-(4-acetyl-3,5-dimethyl-1H-pyrazol-1-yl)-N-[1-(2-methoxybenzyl)-1H-pyrazol-5-yl]acetamide |
- |
|
2.7.4.22 | 2-amino-8-(2-oxo-2-phenylethoxy)-1,4,5,9-tetrahydro-6H-purin-6-one |
10 micromol, 60 min, room temperature, 75% inhibition, crystal enzyme complex structure, overview |
|
2.7.4.22 | 2-amino-8-hydroxy-1,4,5,9-tetrahydro-6H-purin-6-one |
10 micromol, 60 min, room temperature, 18% inhibition |
|
2.7.4.22 | 2-amino-8-[2-(2-methylphenyl)-2-oxoethoxy]-1,4,5,9-tetrahydro-6H-purin-6-one |
10 micromol, 60 min, room temperature, 48% inhibition |
|
2.7.4.22 | 2-amino-8-[2-(3-methylphenyl)-2-oxoethoxy]-1,4,5,9-tetrahydro-6H-purin-6-one |
10 micromol, 60 min, room temperature, 77% inhibition |
|
2.7.4.22 | 2-amino-8-[2-(4-fluorophenyl)-2-oxoethoxy]-1,4,5,9-tetrahydro-6H-purin-6-one |
10 micromol, 60 min, room temperature, 73% inhibition |
|
2.7.4.22 | 2-amino-8-[2-(4-hydroxyphenyl)-2-oxoethoxy]-1,4,5,9-tetrahydro-6H-purin-6-one |
10 micromol, 60 min, room temperature, 77% inhibition |
|
2.7.4.22 | 2-amino-8-[2-(4-methoxyphenyl)-2-oxoethoxy]-1,4,5,9-tetrahydro-6H-purin-6-one |
10 micromol, 60 min, room temperature, 74% inhibition |
|