EC Number |
Inhibitors |
Structure |
---|
4.1.1.50 | (1E)-1-(9-bromo-3-phenanthryl)ethanone oxime |
75% inhibition at 0.1 mM |
|
4.1.1.50 | (2E)-2-[(2E)-2-[(diaminomethyl)hydrazono]-1-methylethylidene]hydrazinecarboximidamide |
i.e. MGBG, active site inhibitor |
|
4.1.1.50 | (2E)-2-[4-[amino(imino)methyl]-2,3-dihydro-1H-inden-1-ylidene]hydrazinecarboximidamide |
i.e. CGP 48664A, stimulation in the range of 0.1-10 microM, inhibition at higher comcentration. Binds to the putrescine binding site and to the active site |
|
4.1.1.50 | (2E)-2-[4-[amino(imino)methyl]-2,3-dihydro-1H-inden-1-ylidene]hydrazinecarboximidamide |
i.e. CGP48664A, SAM486A, active site inhibitor, in addition suppresses HIV-1 replication |
|
4.1.1.50 | (2R,3R,4R,5R)-2-([[(2Z)-4-aminobut-2-en-1-yl](methyl)amino]methyl)-5-(6-amino-9H-purin-9-yl)-4-fluorotetrahydrofuran-3-ol |
- |
|
4.1.1.50 | (2R,3R,4S,5R)-2-([[(2Z)-4-aminobut-2-en-1-yl](methyl)amino]methyl)-5-(6-amino-9H-purin-9-yl)-4-fluorotetrahydrofuran-3-ol |
- |
|
4.1.1.50 | (2R,3S,4R,5R)-2-([[(2Z)-4-aminobut-2-en-1-yl](methyl)amino]methyl)-5-(6-amino-2-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diol |
- |
|
4.1.1.50 | (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt |
competitive with respect to S-adenosylmethionine; i.e. decarboxylated S-adenosylmethionine |
|
4.1.1.50 | (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt |
irreversible |
|
4.1.1.50 | (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt |
- |
|