EC Number |
Metals/Ions |
Reference |
---|
1.2.1.105 | ADP |
activates through allosteric binding |
676088 |
1.2.1.105 | Ca2+ |
- |
656591, 672280, 758747 |
1.2.1.105 | Ca2+ |
0.01 mM, decreases the concentration of 2-oxoglutarate required for half-maximal activity, inhibition at higher concentrations |
349038 |
1.2.1.105 | Ca2+ |
3.5 mol of Ca2+-binding sites per mol of 2-oxoglutarate dehydrogenase complex |
349001 |
1.2.1.105 | Ca2+ |
activates |
348910, 349006, 349026 |
1.2.1.105 | Ca2+ |
activates the 2-oxoglutarate dehydrogenase complex activity |
656580 |
1.2.1.105 | Ca2+ |
Ca2+ and Mg2+ together synergistically reduce the Km-value for 2-oxoglutarate by over 10fold |
349042 |
1.2.1.105 | Ca2+ |
dependent on |
676088 |
1.2.1.105 | Ca2+ |
dependent on, activates through allosteric binding |
676088 |
1.2.1.105 | Ca2+ |
diminishes the Km value of the 2-oxoglutarate dehydrogenase complex for 2-oxoglutarate in the physiological range, maximal activation, 35%, with 0.004 mM Ca2+ |
349003 |