EC Number   |
Metals/Ions |
Reference |
|---|
    1.2.7.11 | 4Fe-4S center |
the enzyme has one [4Fe4S]2+ cluster, ligated by 4 Cys residues, C12, C15, C46, and C197. All four Cys are required to fold a [4Fe4S] cluster for oxidative decarboxylation of pyruvate including the formation of a stable hydroxyethyl-thiamine diphosphate radical |
724470 |
| 1.2.7.11 | Iron |
contains one [4Fe-4S]2+,1+ cluster per alpha/beta structure |
288435 |
| 1.2.7.11 | Iron |
intact enzyme molecule contains two [4Fe-4S](2+,1+) clusters |
288417 |
| 1.2.7.11 | iron-sulfur centre |
the enzyme contains one [4Fe-4S]2+,1+ cluster |
725876 |
| 1.2.7.11 | Mg2+ |
contains 1.4 mol of Mg per mol of protein |
288435 |
| 1.2.7.11 | Mg2+ |
contains two Mg2+ per dimer |
725876 |
| 1.2.7.11 | Mg2+ |
natural enzyme: 1.4 mol/mol, recombinant enzyme 1.9 mol/mol |
719399 |
| 1.2.7.11 | Mg2+ |
required |
739701 |
