EC Number   |
Metals/Ions |
Reference |
|---|
    3.5.1.9 | Cd2+ |
active site-bound |
733300 |
| 3.5.1.9 | Co3+ |
15-20fold activation |
664978 |
| 3.5.1.9 | Mn2+ |
15-20fold activation |
664978 |
| 3.5.1.9 | more |
cations occupy a crowded environment, and, unlike most Zn2+ -dependent enzymes, there is little scope to increase co-ordination number during catalysis |
733300 |
| 3.5.1.9 | more |
no activation by Mg2+, Cu2+ and Ni3+ |
664978 |
| 3.5.1.9 | more |
presence of Cd2+ and Zn2+ in the active site of, cations occupy a crowded environment, and, unlike most Zn2+ -dependent enzymes, there is little scope to increase co-ordination number during catalysis |
733300 |
| 3.5.1.9 | Zn2+ |
required |
733183 |
| 3.5.1.9 | Zn2+ |
required, the enzyme contains a crowded binuclear zinc catalytic site primed to generate a potent nucleophile, a highly organized and distinctive binuclear Zn2+ catalytic centre in a confined, hydrophobic and relatively rigid active site |
733300 |
