EC Number   |
Natural Substrates   |
---|
  1.3.1.72 | 24-methylenecholesterol + NADPH + H+ |
- |
  1.3.1.72 | 5alpha-cholest-7-en-3beta-ol + NADP+ |
- |
  1.3.1.72 | 5alpha-cholesta-7,24-dien-3beta-ol + NADPH |
C-24 reduction of sterols probably takes place straight after sterol DELTA8-7 isomerization of zymosterol, which occurs several steps after C-32 demethylation of lanosterol in the 19-step pathway of cholesterol biosynthesis from lanosterol |
  1.3.1.72 | 5alpha-cholesta-7,24-dien-3beta-ol + NADPH |
C-24 reduction of DELTA7,24-diene |
  1.3.1.72 | 5alpha-cholesta-7,24-dien-3beta-ol + NADPH |
most reactive, probably natural substrate |
  1.3.1.72 | 5alpha-cholesta-7,24-dien-3beta-ol + NADPH |
2 major alternate routes for cholesterol biosynthesis, step in the biosynthesis of cholesterol from lanosterol |
  1.3.1.72 | 5alpha-cholesta-7,24-dien-3beta-ol + NADPH |
step in the biosynthesis of cholesterol from lanosterol |
  1.3.1.72 | cholesta-5,24-dien-3beta-ol + NADPH + H+ |
- |
  1.3.1.72 | cholesta-5,24-dien-3beta-ol + NADPH + H+ |
reduction of desmosterol to cholesterol is dependent on FAD |
  1.3.1.72 | cholesta-5,7,24-trien-3beta-ol + NADPH |
step in the biosynthesis of cholesterol from desmosterol |