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bifunctional enzyme catalyzing the formation of 5,10-methylene tetrahydrofolate and the oxidation of N,N-dimethylglycine, folate binding and active site, a large channel connects both active sites, the channeling is kinetically controlled by terahydrofolate binding, overview
N,N-dimethylglycine + H2O + O2
involved in tetrahydrofolate-dependent assimilation of methyl groups