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Results 1 - 4 of 4
EC Number
Natural Substrates
Commentary (Nat. Sub.)
2,4,6-trinitrotoluene + NADH + H+
-
2,4,6-trinitrotoluene + NADPH + H+
-
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Escherichia coli nitroreductase NfsB can reduce nitrochloromethylbenzindolines, i.e. nitro-CBIs, in an oxygen-independent fashion, generating highly cytotoxic metabolites that alkylate the N3 of adenine in the minor groove of DNA
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Pseudomonas aeruginosa nitroreductase NfsB can reduce nitrochloromethylbenzindolines, i.e. nitro-CBIs, in an oxygen-independent fashion, generating highly cytotoxic metabolites that alkylate the N3 of adenine in the minor groove of DNA
Results 1 - 4 of 4