Refine search

Search Natural Substrates/ Products (Substrates)

Natural Substrates/ Products (Substrates): show results

Don't show organism specific information (fast!)

Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)

(Not possible to combine with the first option)

Refine your search

Recommended Name:

EC Number:

Organism:

Commentary (Nat. Sub.):

Natural Products:

Commentary (Nat. Pro.):

Reversibility:

Search for synonyms (with exact matching search term)

Search term:

Results 1 - 8 of 8

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.7.1.B2	2,4,6-trinitrotoluene + NADH + H+	-
1.7.1.B2	2,4,6-trinitrotoluene + NADPH + H+	-
1.7.1.B2	2,4-dinitrotoluene + NADPH + H+	-
1.7.1.B2	2,6-dinitrotoluene + NADPH + H+	-
1.7.1.B2	more	Escherichia coli nitroreductase NfsB can reduce nitrochloromethylbenzindolines, i.e. nitro-CBIs, in an oxygen-independent fashion, generating highly cytotoxic metabolites that alkylate the N3 of adenine in the minor groove of DNA
1.7.1.B2	2,4-dinitrotoluene + NADPH + H+	highest activity
1.7.1.B2	2,6-dinitrotoluene + NADPH + H+	highest activity
1.7.1.B2	more	Pseudomonas aeruginosa nitroreductase NfsB can reduce nitrochloromethylbenzindolines, i.e. nitro-CBIs, in an oxygen-independent fashion, generating highly cytotoxic metabolites that alkylate the N3 of adenine in the minor groove of DNA

Results 1 - 8 of 8

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)