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Results 1 - 8 of 8

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.7.1.B2	2,4,6-trinitrotoluene + NADH + H+	-
1.7.1.B2	2,4,6-trinitrotoluene + NADPH + H+	-
1.7.1.B2	2,4-dinitrotoluene + NADPH + H+	-
1.7.1.B2	2,4-dinitrotoluene + NADPH + H+	highest activity
1.7.1.B2	2,6-dinitrotoluene + NADPH + H+	-
1.7.1.B2	2,6-dinitrotoluene + NADPH + H+	highest activity
1.7.1.B2	more	Escherichia coli nitroreductase NfsB can reduce nitrochloromethylbenzindolines, i.e. nitro-CBIs, in an oxygen-independent fashion, generating highly cytotoxic metabolites that alkylate the N3 of adenine in the minor groove of DNA
1.7.1.B2	more	Pseudomonas aeruginosa nitroreductase NfsB can reduce nitrochloromethylbenzindolines, i.e. nitro-CBIs, in an oxygen-independent fashion, generating highly cytotoxic metabolites that alkylate the N3 of adenine in the minor groove of DNA

Results 1 - 8 of 8

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Release 2023.1 (January 2023)