EC Number |
Natural Substrates |
---|
1.1.1.145 | 17alpha-hydroxypregnenolone + NAD+ |
- |
1.1.1.145 | 5-pregnen-3beta-ol-2-one + NAD+ |
- |
1.1.1.145 | 5-pregnen-3beta-ol-2-one + NAD+ |
trivial name pregnenolone |
1.1.1.145 | androstenone + NAD+ |
- |
1.1.1.145 | androstenone + NADH |
- |
1.1.1.145 | dehydroepiandrosterone + NAD+ |
- |
1.1.1.145 | dehydroepiandrosterone + NAD+ |
isozyme type 1 |
1.1.1.145 | dehydroepiandrosterone + NADH + H+ |
- |
1.1.1.145 | DELTA5-3beta-hydroxysteroid + NAD+ |
the enzyme is essential for biosynthesis of all classes of steroid hormones |
1.1.1.145 | DELTA5-3beta-hydroxysteroid + NAD+ |
the enzyme is essential for biosynthesis of all classes of steroid hormones, molecular mechanisms of enzyme regulation involving the Nur77 family of immediate-early orphan nuclear receptors, e.g. Nur77 targets the promoter of gene HSD3B2 in testicular Leygig cells, overview |