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Results 1 - 3 of 3

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.4.99.5	glycine + FAD	glycine is decarboxylated to HCN by the enzyme HCN synthase, the product of the hcnABC synthase gene cluster
1.4.99.5	glycine + O2	-
1.4.99.5	more	cyanide produced by the enzyme is involved in virulence of the organism. Drosophila melanogaster exposed to cyanogenic Pseudomonas aeruginosa strains have high cyanide and low ATP concentrations in body extracts, and treatment with a cyanide antidote equalized survival of flies injected with cyanogenic and noncyanogenic strains. Strain PAO1 with a mutation in the hydrogen cyanide synthase gene cluster is much less toxic to flies than the parental cyanogenic strain or 2 knock-in strains, overview

Results 1 - 3 of 3

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Release 2023.1 (January 2023)