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Results 1 - 10 of 19

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.5.1.33	2 biopterin + 3 NADPH + 3 H+	essential enzyme of pterin and folate metabolism
1.5.1.33	2 biopterin + 3 NADPH + 3 H+	salvage of pterins, enzyme acts as a metabolic bypass for drugs targeting dihydrofolate reductase, PTR1 contributes about 10% of the reduction of folates in wild-type cells while the remaining 90% is due to the activity of dihydrofolate reductase-thymidylate synthase (EC 1.5.1.3)
1.5.1.33	6-biopterin + NADPH + H+	-
1.5.1.33	7,8-dihydrobiopterin + NADPH + H+	-
1.5.1.33	7,8-dihydrobiopterin + NADPH + H+	best substrate
1.5.1.33	7,8-dihydrofolate + NADPH + H+	-
1.5.1.33	biopterin + 2 NADPH + 2 H+	-
1.5.1.33	biopterin + NADPH + H+	-
1.5.1.33	dihydrobiopterin + NADPH + H+	-
1.5.1.33	folate + NADPH + H+	-

Results 1 - 10 of 19

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Release 2023.1 (January 2023)