EC Number |
Natural Substrates |
---|
1.8.4.12 | calmodulin-L-methionine (R)-sulfoxide + thioredoxin |
- |
1.8.4.12 | calmodulin-L-methionine (R)-sulfoxide + thioredoxin |
MsrB is specific for the R-form, enzyme provides protection against oxidative damage by reactive oxygen species and has a repair function for oxidized protein methionine residues, which restores the calmodulin binding to adenylate cyclase of the pathogen Bordetella pertussis, which is an essential step for the bacterium to enter host cells, overview |
1.8.4.12 | Hsp21 L-methionine S-oxide + dithiothreitol |
chloroplast-localized small heat shock protein, repair function for heat shock protein Hsp21 by restoring the structure, which is crucial for cellular resistance to oxidative stress, the enzyme can protect the chaperone-like activity of Hsp21 |
1.8.4.12 | L-methionine (R)-S-oxide + thioredoxin |
- |
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin |
- |
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin |
enzyme form MsrB is specific for the R-form, enzyme form variants with specificities for either free or protein-bound methionine |
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin |
enzyme is involved in repairing of oxidized methionine residues in proteins |
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin |
important antioxidant enzyme and colonization factor in the gastric pathogen, a methionine repair enzyme responsible for stress resistance |
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin |
membrane-bound enzyme form Mem-R,S-Msr, enzyme form MsrB is specific for the R-form, MsrB enzyme form variants with specificities for either free or protein-bound methionine, Mem-R,S-Msr also posesses MsrA activity utilizing L-methionine (S)-sulfoxide as substrate |
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin |
Msr is specific for the R-isomer |