EC Number   |
Natural Substrates |
|---|
    2.7.1.25 | ATP + adenosine 5'-phosphosulfate |
involved in the synthesis of the important sulfate donor 3'-phosphoadenosine 5'-phosphosulfate from ATP and sulfate, inactivating mutations of PAPSS2 causes skeletal disorders |
| 2.7.1.25 | ATP + adenosine 5'-phosphosulfate |
synthesis of the important sulfate donor 3'-phosphoadenosine 5'-phosphosulfate from ATP and sulfate |
| 2.7.1.25 | ATP + adenosine 5'-phosphosulfate |
synthesis of the important sulfate donor 3'-phosphoadenosine 5'-phosphosulfate from ATP and sulfate, decreased activity leads to defects in skeleton |
| 2.7.1.25 | ATP + adenosine 5'-phosphosulfate |
synthesis of the important sulfate donor 3'-phosphoadenosine 5'-phosphosulfate from ATP and sulfate, enzyme defect causes brachymorphism, a severe growth disorder affecting skeletal elements as well as other physiological processes |
| 2.7.1.25 | ATP + adenosine 5-phosphosulfate |
ultimate step in biosynthesis of 3'-phosphoadenosine 5'-phosphosulfate, the primary biological sulfuryl donor |
| 2.7.1.25 | ATP + adenosine 5-phosphosulfate |
second step in pathway of assimilation of inorganic sulfate |
| 2.7.1.25 | ATP + adenosine 5-phosphosulfate |
enzyme is involved in sulfation of cartilaginous chondroitin sulfate, reduced enzyme activity causes brachymorphism |
| 2.7.1.25 | ATP + adenosine 5-phosphosulfate |
PAPSS 1 is essential for the sulfonation of mucin like glycoproteins such as GlyCAM-1, CD34 and MAdCAM-1 in high endothelial venules |
| 2.7.1.25 | ATP + adenosine 5-phosphosulfate |
enzyme is involved in cysteine synthesis and sulfate assimilation, enzyme is required for activity of the avirulence rice resistant protein AvrXa21 |
| 2.7.1.25 | ATP + adenosine-5'-phosphosulfate |
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