EC Number   |
Natural Substrates |
|---|
   3.1.21.3 | DNA + H2O |
R.HpyAXII effectively restricts chromosomal DNA during natural transformation |
| 3.1.21.3 | duplex DNA + ATP |
- |
| 3.1.21.3 | duplex DNA + ATP |
type I enzymes recognize bipartite DNA sequences comprising two half-sequences separated by a gap, for example, AACNNNNNNGTGC (AAC N6 GTGC) where N=any base |
| 3.1.21.3 | linear plasmid DNA pDRM-2R + ATP |
- |
| 3.1.21.3 | more |
- |
| 3.1.21.3 | more |
restricts unmodified phage DNA after both infection and transfection |
| 3.1.21.3 | more |
a bacterial population may switch the recognition sequence of its type I restriction-modification system by single recombination events and thus is able to maintain a prokaryotic analogue of the immune system of variable specificity |
| 3.1.21.3 | more |
enzyme restricts the exchange of genetic material between bacteria of different strains or species |
| 3.1.21.3 | more |
isoform Sau1 is the major mechanism for blocking transfer of resistance genes and other mobile genetic elements into Staphylococcus aureus isolates from other species, as well as for controlling the spread of resistance genes between isolates of different Staphylococcus aureus lineages |
| 3.1.21.3 | more |
basal transcription from promoter esp1396ICR results in gradual accumulation of C.Esp1396I, which upon dimerization binds to a single site in promoter esp1396IM, preventing further transcription from this promoter. Further accumulation of C.Esp1396I results in activation and then gradual repression of promoter esp1396ICR |
