EC Number   |
Natural Substrates |
|---|
    3.5.4.16 | GTP + H2O |
- |
| 3.5.4.16 | GTP + H2O |
first committed step in the biosynthesis of tetrahydrofolate and tetrahydrobiopterin |
| 3.5.4.16 | GTP + H2O |
rate-limiting enzyme in the biosynthesis of tetrahydrobiopterin, important in the regulation of monoamine neurotransmitters such a s dopamine, norepinephrine, and serotonin |
| 3.5.4.16 | GTP + H2O |
rate-limiting step in the biosynthesis of tetrahydrobiopterin, a key factor necessary for nitric oxide synthase, and for the hydrolxylases that are involved in the production of catecholamines and serotonin |
| 3.5.4.16 | GTP + H2O |
the enzyme mediates the first and committing step of the pterin branch of the folate-synthesis pathway |
| 3.5.4.16 | GTP + H2O |
the enzyme mediates the first and committing step pf the pterin branch of the folate-synthesis pathway |
| 3.5.4.16 | GTP + H2O |
the enzyme mediates the first and committing step of the pterin branch of the folate-synthesis pathway |
| 3.5.4.16 | GTP + H2O |
estrogens play a regulatory role on the enzyme expression, the enzyme is involved in estrogen receptor interaction with cyclic AMP, role of receptor subtypes, overview |
| 3.5.4.16 | GTP + H2O |
first step in the biosynthesis pathway leading to dihydrofolate and tetrahydrobiopterin |
| 3.5.4.16 | GTP + H2O |
the enzyme controls the biosynthesis pathway of tetrahydrobiopterin, which is a necessary cofactor for inducible nitric oxide synthase |
