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EC Number Application Commentary Reference
Display the reaction diagram Show all sequences 1.1.1.B18pharmacology the enzyme produces double chiral aminoalcohols, which are used as pharmaceuticals. The Rhodococcus expression vector, pRET11100, constructed by removing aadh from the pRET1172 plasmid may be useful for bioconversion -, 762822
Display the reaction diagram Show all sequences 1.1.1.B18synthesis coversion of 1-(3-hydroxyphenyl)-2-(methylamino) ethanone to (S)-phenylephrine with with more than 99% enantiomeric excess, 78% yield and a productivity of 3.9 mmol(S)-phenylepinephrine/l h in 12 h at 30°C and pH 7. The (S)-phenylepinephrine, recovered from reaction mixture by precipitation at pH 11.3, can be converted to (R)-phenylepinephrine by Walden inversion reaction -, 713441
Results 1 - 2 of 2