EC Number   |
Application  |
Reference |
|---|
   2.4.1.210 | agriculture |
gene sequence of limonoid UDP-glucosyltransferase in citrus fruits with different bitterness do not vary but the pattern of expression, delayed bitterness is related to delay in expression of the limonoid glucosyltransferase gene |
684923 |
| 2.4.1.210 | agriculture |
whether the CitLGT-2 is present or not, is a useful molecular indicator for predetermining the levels of accumulation of non-bitter limonoid glucosides at the early- to mid-developmental stages of Satsuma mandarin and navel orange fruits. These molecular indicators will make it possible to characterize fruit traits at the seedling stage, resulting in the marker-assisted selection of hybrid progenies to predetermine whether they will accumulate non-bitter limonoid glucosides |
658581 |
| 2.4.1.210 | food industry |
Citxadrus limonoid glucosyltransferase which is a key playxader for natural debitterness and anticancerous potenxadtial, can be utilized for metabolic engineering of Citxadrus limonoids to get rid of delayed bitterness problem along with enhanced limonoid glucoside molecules. The presence or absence of LGT can serve as a molecxadular indicator for determining the level of accumulaxadtion of limonoid glucoside and may reflect ultimately the possibility of delayed bitterness in available Citrus germplasm. Enhanced activity of LGT in citrus fruits may increase the glucoside level, which in turn will reduce the bitterness problem |
759285 |
| 2.4.1.210 | food industry |
Limonoid glucosyltransferase is an enzyme that catalyzes the conversion of bitter limonoid into non-bitter limonoid glucoside while retaining the health benefit of limonoids in the juice. The immobilization of this enzyme in a column can solve the juice bitterness problem |
722071 |
| 2.4.1.210 | food industry |
major problem in the orange industry is delayed bitterness, which is caused by limonin, a bitter compound developing from its non-bitter precursor limonoate A-ring lactone (LARL) during and after extraction of orange juice. The glucosidation of LARL by limonoid UDP-glucosyltransferase (LGT) to form non-bitter glycosyl-limonin during orange maturation has been demonstrated as a natural way to debitter by preventing the formation of limonin. Enzyme LGT activity can be used to develop biotechnology-based approaches for producing orange juice from varietals that traditionally have a delayed bitterness |
759676 |
| 2.4.1.210 | food industry |
overexpression of the LGT gene can reduce the delayed bitterness problem in citrus juice |
759215 |
| 2.4.1.210 | medicine |
Citxadrus limonoid metabolic engineering, and extraction as well as utilization of bioactive limonoids for health promoting and disease-preventing benefits. Limonoids are present in a very high amount in Citrus seeds and peel and thus their extractions can have commercial value. Limonoid aglycones and a mixture of limonoid glucosides are administered in human breast cancer cell lines. It has been demonstrated that limonoids are more potent than tamoxifen for estrogen-independent breast cancer cells and equally potent as tamoxifen for estrogen-dependent breast cancer cells. Effects and mechanisms of limonoids on cancer cells, overview. The Citrus limonoids such as obacunone, limonin, nomilxadin and their glucosides and some aglycones are found to have cytotoxic effects against lung, oral and skin cancers in animal test system and human breast cancer cells |
759285 |
| 2.4.1.210 | medicine |
overexpression of the LGT gene can enhance the accumulation of specific glucosides that have anticancer effects. Citrus limoxadnoids, specifically limonoid glucosides, which are the prodxaduct of glucosyltransferase enzyme, are water-soluble and have good bioavailability and non-toxic effects in animals and huxadmans. Thus, they can easily be used as nutraceuticals and health fortifiers in many functional foods |
759215 |
| 2.4.1.210 | medicine |
pharmacological application of limonoid GTase gene |
288691 |
| 2.4.1.210 | nutrition |
- |
288691 |
