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Results 1 - 8 of 8
EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.12analysis because the content of enzyme, irrespective of the cause of alteration, is correlated with fertility-related parameters, PHGPx can be considered a predictive measure for fertilization capacity 658247
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.12medicine MPHGPx transgenic mice made diabetic by multiple low-dose streptozotocin injections show decreased ejection fraction and fractional shortening in diabetic hearts that is reversed with hydroperoxide glutathione peroxidase mPHDPx4 overexpression. MPHGPx overexpression increases electron transport chain function while attenuating hydrogen peroxide production and lipid peroxidation in diabetic mPHGPx interfibrillar mitochondria. mPHGPx overexpression lessens proteomic loss observed in diabetic interfibrillar mitochondria. Posttranslational modifications, including oxidations and deamidations, are attenuated with mPHGPx overexpression. Mitochondrial protein import dysfunction in diabetic interfibrillar mitochondria is reversed with mPHGPx overexpression correlating with protein import constituent preservation. Oxidative phosphorylation, tricarboxylic acid cycle, and fatty acid oxidation processes most influenced in diabetic interfibrillar mitochondria are preserved by mPHGPx overexpression 723911
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.12medicine overexpression of GPx4 inhibits the development of atherosclerosis by decreasing lipid peroxidation and inhibiting the sensitivity of vascular cells to oxidized lipids 698045
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.12medicine PHGPx downregulation could be related with a poorer prognosis in breast invasive ductal carcinoma 686896
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.12medicine PHGPx is useful as a biomarker to screen for detrimental effects of exogenous endocrine disrupting chemicals in testes 688724
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.12medicine tumor growth inhibitor 673931
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.12more an assay for sperm PHGPx activity emerges as a unique tool to evaluate semen quality for sire selection 701272
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.12more comparative analysis of invertebrate GPx genes provides information evidence to support the modular pathways of GPx evolution, which have been accompanied with sporadic expansion-deletion and exon-intron remodeling, the study would be beneficial to get detailed insights into the complex GPx evolution, and to understand the molecular basis of the specialized physiological implications of the antioxidant system in their respective organisms 696970
Results 1 - 8 of 8