EC Number |
Application |
Reference |
---|
4.1.1.37 | agriculture |
first step to establish this enzyme as a possible biomarker for environmental contamination |
-, 650890 |
4.1.1.37 | diagnostics |
uroporphyrinogen decarboxylase activity has a high diagnostic accuracy for differentiating the 2 Porphyria cutanea tarda types, the sporadic (sPCT) and familial (fPCT) forms, which are generally clinically indistinguishable, a model that takes into account both clinical information and laboratory test results can be used to predict fPCT |
703269 |
4.1.1.37 | medicine |
a low erythrocytic UROD may be a predisposing factor for porphyria cutanea tarda |
691975 |
4.1.1.37 | medicine |
malfunction of UROD is associated with porphyria cutanea tarda and hepatoerythropoietic porphyria, denaturing gradient gel electrophoresis technique DGGE assay presents genetic diagnosis method for screening patients from previously uncharacterized families, differential diagnosis between familial and sporadic cases of PCT |
651454 |
4.1.1.37 | medicine |
PCT is a human metabolic disorder, due to the acquired or genetic impairment of uroporphyrinogen decarboxylase activity |
650797 |
4.1.1.37 | medicine |
subnormal activity of uroporphyrinogen decarboxylase in hepatocytes is responsible for the most common form of porphyria in humans, porphyria cutanea tarda |
650726 |
4.1.1.37 | medicine |
the clinical manifestations of Porphyria cutanea tarda in dialysis patients can be a result of reduced activity of uroporphyrinogen decarboxylase in addition to the accumulation of photosensitive by-products resulting from a lack of an effective means of excretion |
706767 |
4.1.1.37 | medicine |
uroporphyrinogen decarboxylase is a radiosensitizing target for head and neck cancer |
716915 |