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EC Number Posttranslational Modification Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.95side-chain modification alpha-aminoadipate reductase Lys2 is posttranslationally activated by phosphopantetheinyl transferase Lys5 which transfers a phosphopantetheinyl group from coenzyme A to Lys2. Activation is required for catalytic activity 288204
Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.95side-chain modification enzyme Lys1 is active when expressed in Escherichia coli and exhibits significant alpha-aminoadipate reductase activity without the addition of CoA or Schizosaccharomyces pombe phosphopantetheinyl transferase 657420
Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.95side-chain modification residue Ser880 is modified by phosphopantetheinylate, leading to activiation of the enzyme. Protein Lys5 catalyzes the modification using coenzyme A 288201
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