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Results 1 - 4 of 4
EC Number
Reaction
Commentary
Reference
(R)-pantoate + NADP+ = 2-dehydropantoate + NADPH + H+
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(R)-pantoate + NADP+ = 2-dehydropantoate + NADPH + H+
molecular catalytic mechanism, substrate and cofactor binding, Asn98, Glu256, and Lys176 are essential, overview
(R)-pantoate + NADP+ = 2-dehydropantoate + NADPH + H+
protein-ligand interactions, overview
(R)-pantoate + NADP+ = 2-dehydropantoate + NADPH + H+
the enzyme follows a random addition mechanism in which the initial binding of NADPH is the kinetically preferred path, with a small degree of cooperativity between subunits. The mechanism of Staphylococcus aureus KPR is distinct from those of previously described members of the family of 2-hydroxyacid dehydrogenases
Results 1 - 4 of 4