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Results 1 - 4 of 4
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EC Number Reaction Commentary Reference
Show all pathways known for 1.1.1.286Display the reaction diagram Show all sequences 1.1.1.286(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+ - -
Show all pathways known for 1.1.1.286Display the reaction diagram Show all sequences 1.1.1.286(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+ chemical mechanism on the basis of the pH dependence of kinetic parameters, dissociation constants for competitive inhibitors, and multiple-substrate deuterium/13C isotope effects suggesting a stepwise mechanism with hydride transfer preceding decarboxylation, the decarboxylation step contributes only slightly to rate limitation, overview 685232
Show all pathways known for 1.1.1.286Display the reaction diagram Show all sequences 1.1.1.286isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+ - -
Show all pathways known for 1.1.1.286Display the reaction diagram Show all sequences 1.1.1.286isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+ chemical mechanism on the basis of the pH dependence of kinetic parameters, dissociation constants for competitive inhibitors, and multiple-substrate deuterium/13C isotope effects suggesting a stepwise mechanism with hydride transfer preceding decarboxylation, the decarboxylation step contributes only slightly to rate limitation, overview 685232
Results 1 - 4 of 4
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