EC Number   |
Reaction |
Reference  |
|---|
   1.14.13.16 | cyclopentanone + NADPH + H+ + O2 = 5-valerolactone + NADP+ + H2O |
- |
- |
| 1.14.13.16 | cyclopentanone + NADPH + H+ + O2 = 5-valerolactone + NADP+ + H2O |
reaction mechanism via key intermediate flavin C4a-peroxide, involving the four-electron reduction of O2 at the expense of a two-electron oxidation of NADPH and a two-electron oxidation of cyclohexanone to epsilon-caprolactone, overview |
-, 675582 |
| 1.14.13.16 | cyclopentanone + NADPH + H+ + O2 = 5-valerolactone + NADP+ + H2O |
residues Phe450 and Phe156 are important for reaction stereospecificity |
-, 677179 |
| 1.14.13.16 | cyclopentanone + NADPH + H+ + O2 = 5-valerolactone + NADP+ + H2O |
the reaction mechanism of BVMO with native substrate phenylacetone proceeds via the formation of a Criegee intermediate with anionic character, which is subsequently rearranged via the migration of alkyl group to yield the product ester, reaction mechanism, overview |
765535 |
