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Results 1 - 4 of 4
EC Number Reaction Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.159cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate + NADH + H+ belongs to the short-chain dehydrogenase/reductase 1 familiy (SDR), mechanism 286081
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.159cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate + NADH + H+ catalyses the oxidation of the 7alpha-hydroxyl group of bile acids and alcohols both in their free and conjugated forms. The Bacteroides fragilis and Clostridium enzymes can also utilize NADP+ -
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.159cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate + NADH + H+ short-chain dehydrogenase group 286084
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.159cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate + NADH + H+ Tyr159 acts as basic catalyst, Lys163 binds to NAD(H) and lowers the pKa value of Tyr159, Ser146 stabilizes the substrate, reaction intermediate and product in catalysis 286083
Results 1 - 4 of 4