EC Number   |
Reaction |
Reference |
|---|
    1.18.6.1 | 4 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 4 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate |
- |
- |
| 1.18.6.1 | 4 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 4 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate |
active site is located on the MoFe cofactor involving residues alphaR96, alphaG69, alphaV70, and alphaH195 |
-, 658010 |
| 1.18.6.1 | 4 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 4 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate |
active site location |
659426 |
| 1.18.6.1 | 4 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 4 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate |
C2H2 inhibition mechanism, structure model |
440183 |
| 1.18.6.1 | 4 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 4 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate |
catalytic mechanism |
440142, 440144, 440146, 440147, 440149, 440174 |
| 1.18.6.1 | 4 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 4 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate |
enzyme complex dissociation and association kinetics |
440138 |
| 1.18.6.1 | 4 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 4 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate |
enzyme is composed of 2 metalloproteins: component I MoFe protein and component II Fe protein |
-, 440134, 440138, 440140, 440142, 440143, 440144, 440145, 440146, 440147, 440148, 440149, 440150, 440151, 440152, 440153, 440154, 440155, 440156, 440157, 440158, 440159, 440160, 440161, 440162, 440163, 440164, 440165, 440166, 440167, 440168, 440169, 440170, 440171, 440174, 440175, 440177, 440178, 440179, 440180, 440181, 440182, 440183, 440184, 440186, 440187, 440189 |
| 1.18.6.1 | 4 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 4 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate |
Fe protein and MoFe protein are assumed to associate and dissociate to transfer a single electron to the substrates |
440138 |
| 1.18.6.1 | 4 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 4 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate |
first introduction of H at the NFe7MoS9(homocitrate) active site is via a water chain terminating at water 679 to S3B of the my3-S atoms of the active site. Discussion of subsequent movement of the H atoms around the NFe7MoS9(homocitrate) preparatory to the binding and hydrogenation of N2 and other substrates. S2B has a modulatory function and is not an H-entry site |
674147 |
| 1.18.6.1 | 4 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 4 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate |
iron-only enzyme is composed of 2 components: FeFe protein and Fe protein |
-, 440176, 440177 |
