EC Number |
Reaction |
Reference |
---|
1.5.1.38 | FMNH2 + NADP+ = FMN + NADPH + H+ |
- |
- |
1.5.1.38 | FMNH2 + NADP+ = FMN + NADPH + H+ |
ping-pong kinetic pattern |
392200 |
1.5.1.38 | FMNH2 + NADP+ = FMN + NADPH + H+ |
reaction mechanism, overview |
741896 |
1.5.1.38 | FMNH2 + NADP+ = FMN + NADPH + H+ |
the enzyme exhibits double displacement or ping-pong kinetics |
-, 392180 |
1.5.1.38 | FMNH2 + NADP+ = FMN + NADPH + H+ |
the first step in catalysis, which is hydride transfer from C4 of NADPH to cofactor FMN, involves addition to the re face of the FMN, probably at the N5 position. The limited accessibility of the FMN binding pocket and the extensive FMN-protein hydrogen bond network are consistent with the observed ping-pong bisubstrate-biproduct reaction kinetics |
392299 |