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EC Number Reaction Commentary Reference
Show all pathways known for 1.5.99.B2Display the word mapDisplay the reaction diagram Show all sequences 1.5.99.B2L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol also active as 1-pyrroline-5-carboxylate dehydrogenase 392557
Show all pathways known for 1.5.99.B2Display the word mapDisplay the reaction diagram Show all sequences 1.5.99.B2L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor - -
Show all pathways known for 1.5.99.B2Display the word mapDisplay the reaction diagram Show all sequences 1.5.99.B2L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor ping-pong mechanism, the transfer of hydride from L-proline to FAD is rate-limiting for the reductive half-reaction, but the overall reaction is limited by reduced flavin reoxidation in the second half-reaction. Solvent and multiple kinetic isotope effects suggest that L-proline oxidation occurs in a stepwise rather than concerted mechanism -, 741885
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