EC Number |
Reaction |
Reference |
---|
6.3.4.3 | ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate |
direct formylation at the N-10 position, solvent oxygen is not incorporated into N10-formyltetrahydrofolate |
1521 |
6.3.4.3 | ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate |
sequential mechanism, formyl phosphate is an intermediate |
1526 |
6.3.4.3 | ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate |
stepwise mechanism involving a dissociable intermediate, consistent only with a sequential mechanism |
1509 |
6.3.4.3 | ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate |
stepwise reaction mechanism, formyl phosphate is a potential intermediate |
1511 |
6.3.4.3 | ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate |
substrate binds to the enzyme in a random fashion, products are not released until all substrates are bound |
1506 |
6.3.4.3 | ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate |
the enzyme is not trifunctional showing only 10-formyl-THS synthetase activity, enzyme evolutionary considerations |
660817 |