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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
1.14.19.70
744724
Biophysical screening of a focused library for the discovery of CYP121 inhibitors as novel antimycobacterials
ChemMedChem
12
1616-1626
2017
Mycobacterium tuberculosis
28815923
1.14.19.70
744724
Biophysical screening of a focused library for the discovery of CYP121 inhibitors as novel antimycobacterials
ChemMedChem
12
1616-1626
2017
Mycobacterium tuberculosis H37Rv
28815923
1.14.19.70
745367
Cross-linking of dicyclotyrosine by the cytochrome P450 enzyme CYP121 from Mycobacterium tuberculosis proceeds through a catalytic shunt pathway
J. Biol. Chem.
292
13645-13657
2017
Mycobacterium tuberculosis
28667013
1.14.19.70
745176
Probing ligand exchange in the P450 enzyme CYP121 from Mycobacterium tuberculosis Dynamic equilibrium of the distal heme ligand as a function of pH and temperature
J. Am. Chem. Soc.
139
17484-17499
2017
Mycobacterium tuberculosis
29090577
1.14.19.70
746402
QM/MM study of the C-C coupling reaction mechanism of CYP121, an essential cytochrome p450 of Mycobacterium tuberculosis
Proteins
82
1004-1021
2014
Mycobacterium tuberculosis
24356896
1.14.19.70
744721
Substrate fragmentation for the design of M. tuberculosis CYP121 inhibitors
ChemMedChem
11
1924-1935
2016
Mycobacterium tuberculosis
27432475
1.14.19.70
721291
Application of fragment screening and merging to the discovery of inhibitors of the Mycobacterium tuberculosis cytochrome P450 CYP121
Angew. Chem. Int. Ed. Engl.
51
9311-9316
2012
Mycobacterium tuberculosis
22890978
1.14.19.70
721291
Application of fragment screening and merging to the discovery of inhibitors of the Mycobacterium tuberculosis cytochrome P450 CYP121
Angew. Chem. Int. Ed. Engl.
51
9311-9316
2012
Mycobacterium tuberculosis H37Rv
22890978
1.14.19.70
722639
Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450
J. Biol. Chem.
278
5141-5147
2003
Mycobacterium tuberculosis
12435731
1.14.19.70
722639
Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450
J. Biol. Chem.
278
5141-5147
2003
Mycobacterium tuberculosis H37Rv
12435731
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