EC Number   |
General Information |
Reference  |
|---|
   1.1.1.16 | evolution |
LadB belongs to the medium-chain dehydrogenases |
-, 722320 |
| 1.1.1.16 | malfunction |
deletion of ladB in Aspergillus niger results in growth arrest on galactitol and significantly slower growth on D-galactose supplemented with a small amount of D-xylose. D-Galactose alone cannot be utilised by Aspergillus niger and the addition of D-xylose stimulates growth on D-galactose via transcriptional activation of the D-xylose-inducible reductase gene, xyrA |
-, 722320 |
| 1.1.1.16 | metabolism |
LadB catalyzes a step in the oxido-reductive pathway for D-galactose catabolism in filamentous fungi, overview |
-, 722320 |
| 1.1.1.16 | evolution |
galactitol 2-dehydrogenase belongs to the protein subfamily of short-chain dehydrogenases/reductases |
-, 740390 |
| 1.1.1.16 | more |
homology modeling and sequence analysisA , overview. The active site contains residues Asn119,Ser147, Tyr162, and Lys166 which are conserved in short-chain dehydrogenases/reductases |
-, 740390 |
