EC Number   |
General Information  |
Reference |
|---|
    7.1.1.3 | malfunction |
deletion of the cydAB genes for cytochrome bd has no obvious influence on growth, whereas the lack of the cyoBACD genes for cytochrome bo3 severely reduced the growth rate and the cell yield |
725289 |
| 7.1.1.3 | malfunction |
loss of cytochrome bd-I oxidase subunit II (gene cydB) causes diminished respiration rates, impaired motility and enhanced acid resistance. CydB cells contain elevated heme d, particularly at low pH. The GABA/glutamate gadC antiporter is highly up-regulated in cydB cells. Eschrichia coli can compensate for the loss of cytochrome bd-I activity |
-, 715509 |
| 7.1.1.3 | metabolism |
Gluconobacter oxydans oxidizes a variety of substrates in the periplasm by membrane-bound dehydrogenases, which transfer the reducing equivalents to ubiquinone. Two quinol oxidases, cytochrome bo3 and cytochrome bd, then catalyze transfer of the electrons from ubiquinol to molecular oxygen |
725289 |
| 7.1.1.3 | physiological function |
cytochrome bd-II-mediated quinol oxidation prevents the accumulation of NADH, whereas GABA synthesis/antiport maintains the proton motive force for ATP production |
-, 715509 |
| 7.1.1.3 | physiological function |
cytochrome bo is a four-subunit quinol oxidase in the aerobic respiratory chain of Escherichia coli and functions as a redox-coupled proton pump |
-, 714141, 715399 |
| 7.1.1.3 | physiological function |
cytochrome bo-type ubiquinol oxidase in the aerobic respiratory chain of Escherichia coli catalyzes the reduction of dioxygen to water with ubiquinol-8, and utilizes the redox reactions to drive vectorial translocation of protons across the cytoplasmic membrane |
-, 715000 |
| 7.1.1.3 | physiological function |
cytochrome bo3 might be a rate-limiting factor of the respiratory chain |
725289 |
| 7.1.1.3 | physiological function |
cytochrome bo3 ubiquinol oxidase from Escherichia coli is a four-subunit heme-copper oxidase that catalyzes the four-electron reduction of O2 to water and functions as a proton pump |
716311 |
| 7.1.1.3 | physiological function |
cytochrome bo3 ubiquinol oxidase serves as part of a proton loading site that regulates proton translocation across the protein matrix of the enzyme |
714169 |
| 7.1.1.3 | physiological function |
in respiratory mutants, both O2-consumption and aerobic growth are severely impaired by sulfide when respiration is sustained by the bo3 oxidase alone |
752188 |
