EC Number |
General Information |
Reference |
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1.1.1.336 | evolution |
Edwardsiella tarda strains can be grouped into two types of human isolates and diseased fish isolates based on distribution of the wecC gene, type III and type VI secretion system genes, the groups are broadly clustered into two major subpopulations: EdwGI and EdwGII. Edwardsiella tarda EdwGI is composed of strains mainly isolated from fish, such as the turbot, striped bass, and Japanese eel, represents a genotype of fish pathogens, and possesses virulence-associated gene clusters such as T3SS and T6SS. Edwardsiella tarda EdwGII contains strains isolated from human feces, nonpathogenic strains to fish, and environmental strains, and lacks some important virulence-associated gene clusters including T3SS and T6SS |
743240 |
1.1.1.336 | malfunction |
motility activity, including swarming and swimming, of the wecC mutant is weaker than that f the wild-type strain |
743240 |
1.1.1.336 | metabolism |
the enzyme is important for the synthesis of amino sugars and uronic acid and involved in the biosynthesis pathway for the production of polysaccharide bioflocculant, overview |
-, 742145 |
1.1.1.336 | physiological function |
gene wecC is important for survival of Yersinia pestis in murine macrophages |
719745 |
1.1.1.336 | physiological function |
specific knockout mutation in the UDP-D-Nacetylmannosamine dehydrogenase gene, wbpA, results in strains that no longer produce B-band lipopolysaccharide |
719518 |
1.1.1.336 | physiological function |
the enzyme is involved in synthesis of enterobacterial common antigen. The swarming and swimming abilities mediated by the wecC and fliF genes appears to be essential for penetration activity of Edwardsiella tarda through Caco-2 cell monolayers |
743240 |