EC Number   |
General Information |
Reference |
|---|
   1.1.1.366 | malfunction |
gluD deletion results in accumulation of 2-keto-L-gulonate in the liquid cultivation, while the gluE deletion results in reduced growth and cessation of the D-glucuronic acid catabolism |
-, 761153 |
| 1.1.1.366 | metabolism |
in the filamentous fungus Aspergillus niger, the enzymes that are known to be part of the D-glucuronic acid catabolism pathway are the NADPH requiring D-glucuronic acid reductase forming L-gulonate and the NADH requiring 2-keto-L-gulonate reductase that forms L-idonate. With the aid of RNA sequencing two more enzymes of the pathway are identified. The first is a NADPH requiring 2-keto-L-gulonate reductase that forms L-idonate, GluD (EC 1.1.1.264). The second is a NAD+ requiring L-idonate 5-dehydrogenase forming 5-keto-gluconate, GluE. The genes coding for these two enzymes are clustered and share the same bidirectional promoter |
-, 761153 |
| 1.1.1.366 | more |
cultivar Cabernet Sauvignon transcriptome analysis dependent on regional parameters of six different samples, overview. Two unigenes encoding L-idonate dehydrogenase (LidnDH) are detected from the assembled transcriptome. One is expressed higher in Changli region berries than in Gaotai region berries at E-L 31 stage,while the other is expressed higher at E-L 38 stage in Gaotai region berries |
743167 |
| 1.1.1.366 | physiological function |
enzyme LidnDH catalyzes the conversion of L-idonate to 5-keto D-gluconic acid in plant and is proposed to be a rate-limiting step in biosynthesis of tartaric acid from ascorbic acid |
743167 |
