EC Number   |
General Information |
Reference |
|---|
    1.1.99.21 | evolution |
GoSLDH sequencing, structure analyses, and biochemical studies, suggest that it belongs to the NADP+-dependent polyol specific long-chain sorbitol dehydrogenase family. GoSLDH possesses the active site residues of Asp190, Val228, Lys294, and Asp299 and the conserved catalytic motif (KXXXXHXXH) for polyol-specific long-chain dehydrogenase |
-, 741426 |
| 1.1.99.21 | malfunction |
mutation of His302 results in the denaturation of protein structure and loss of stability |
740006 |
| 1.1.99.21 | metabolism |
membrane-bound D-sorbitol dehydrogenase is involved in the biotransformation of D-sorbitol to L-sorbose |
740006 |
| 1.1.99.21 | more |
sequence alignment-based homology modeling using the structure of NAD-bound sorbitol dehydrogenase, EC 1.1.1.14, with UniProt ID Q9KWR5 as template |
740006 |
| 1.1.99.21 | more |
structure comparisons and molecular docking, overview |
-, 741426 |
