EC Number   |
General Information |
Reference |
|---|
    1.3.1.92 | metabolism |
artemisinic aldehyde 11 (13) reductase (DBR2) is the checkpoint enzyme catalyzing artemisinic aldehyde to form dihydroartemisinic aldehyde directly involved in artemisinin biosynthetic pathway |
744537 |
| 1.3.1.92 | metabolism |
the final step of artemisin biosynthesis involves two genes, a double bond reductase (DBR2) and an aldehyde dehydrogenase (ALDH1) |
744971 |
| 1.3.1.92 | physiological function |
the early steps in artemisinin biosynthesis involve amorpha-4,11-diene hydroxylation to artemisinic alcohol, followed by oxidation to artemisinic aldehyde, reduction of the C11-C13 double bond to dihydroartemisinic aldehyde and oxidation to dihydroartemisinic acid |
718241 |
| 1.3.1.92 | physiological function |
the enzyme plays an important role in the biosynthesis of the antimalarial artemisinin in Artemisia annua. The high artemisin producing plant varieties 2/39, Chongqing, and Anamed produce more artemisinin than arteannuin B, while the low artemisin producing plant varieties Meise, Iran#8, Iran#14, Iran#24, and Iran#47 produce more arteannuin B than artemisinin |
746092 |
