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Results 1 - 4 of 4
EC Number General Information Commentary Reference
Show all pathways known for 1.6.3.2Display the reaction diagram Show all sequences 1.6.3.2physiological function in anaerobes, flavin-dependent NAD(P)H oxidases play an important role protecting organisms from oxidative stress 722229
Show all pathways known for 1.6.3.2Display the reaction diagram Show all sequences 1.6.3.2physiological function NAD(P)H oxidase reaction is catalyzed by the native dimeric protein under physiological conditions (low amounts of O2) to detoxify O2. Oxidative stress induced conformational change implicates a functional switch of the enzyme. The oxidized enzyme protein can accelerate the aggregation of partially unfolded proteins. It can also bind nucleic acids and produce H2O2 to destroy DNA and RNA with the ultimate function of decreasing cell viability 723187
Show all pathways known for 1.6.3.2Display the reaction diagram Show all sequences 1.6.3.2physiological function overexpression of this enzyme in Giardia results in significantly enhanced growth under aerobic conditions. NADH oxidase could be thus an instrumental enzyme for the organism to adapt to and to tolerate an aerobic living environment 723205
Show all pathways known for 1.6.3.2Display the reaction diagram Show all sequences 1.6.3.2physiological function the enzyme may be involved in maintenance of an optimum intracellular redox ratio -, 722165
Results 1 - 4 of 4