EC Number   |
General Information |
Reference |
|---|
   2.1.1.113 | metabolism |
cytosine N4-methylation is required for DNA transformation |
-, 735063 |
| 2.1.1.113 | metabolism |
the enzyme is part of the MboII restriction-modification, R-M, system of Moraxella bovis strain ATCC 10900 consisting of a restriction endonuclease gene and two methyltransferase genes |
705556 |
| 2.1.1.113 | metabolism |
the enzyme is part of the Ncul restriction-modification, R-M, system consisting of a restriction endonuclease gene and two methyltransferase genes |
705556 |
| 2.1.1.113 | physiological function |
enzyme recognizes the 5'TCTTC3'x02 sequence and methylates the first cytosine residue. A deletion strain displays lower adherence to host gastric adenocarcinoma cells and reduced potential to induce inflammation and apoptosis. The deletion strain exhibits reduced capacity for natural transformation, and a total of 102 genes belonging to virulence, ribosome assembly and cellular components are differentially expressed |
-, 757851 |
| 2.1.1.113 | physiological function |
enzyme recognizes the motif CCGCGG and methylates the second cytosine residue to give C4mCGCGG. N4-cytosine is the major methylated form in Deinococcus radiodurans. Cells deficient in 4mC modification display higher spontaneous rifampin mutation frequency and enhanced DNA recombination and transformation efficiency. Genes involved in the maintenance of genomic stability are differentially expressed in DraR1 mutant strains |
-, 756780 |
| 2.1.1.113 | physiological function |
mutation of gene sll0729 leads to lowered chlorophyll/phycocyanin ratio and slower growth. Prolonged cultivation reveals instability of the initially obtained phenotype and appearance of suppressor mutants. The suppressor strains show smaller cell size, lowered DNA content per cell, and decreased tolerance against UV compared to wild type. Suppressor cells show decreased levels of DNA topoisomerase 4 subunit A |
756778 |
