EC Number |
General Information |
Reference |
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2.4.1.210 | evolution |
limonoids are highly oxygenated triterpenes present mostly in Rutaceae and other limited plants of Meliaceae and Simaroubaceae, tissue distribution, overview |
759285 |
2.4.1.210 | evolution |
limonoids are highly oxygenated triterpenes present mostly in Rutaceae and other limited plants of Meliaceae and Simaroubaceae, tissue distribution, overview. Limonoid glucosyltransferases belong to the family of glycosyltransferases. Two alleles (CitLGT1/ CitLGT2) of LGT at a single locus which are related to the dexadlayed bitterness in Citrus. The CitLGT2 differs from CitLGT1 by 15 nucleotide substitutions and these subxadstitutions are scattered throughout the coding region of the gene |
759285 |
2.4.1.210 | evolution |
limonoids are highly oxygenated triterpenes present mostly in Rutaceae and other limited plants of Meliaceae and Simaroubaceae, tissue distribution, overview. Limonoid glucosyltransferases belong to the family of glyxadcosyltransferases |
759285 |
2.4.1.210 | evolution |
the enzyme belongs to clade C of flavonoid and limonoid glucosyltransferases |
736296 |
2.4.1.210 | evolution |
the enzyme belongs to the superfamily PLN03004 (UDP-glycosyltransferase). Citrus reticulata limonoid glucosyltransferase (CrLGT) occupies a position on an independent branch in the largest subgroup and is phylogenetically different from those in other mandarin species like Citrus unshiu, showing its uniqueness in several features |
759215 |
2.4.1.210 | malfunction |
overexpression of the LGT gene can reduce the delayed bitterness problem in citrus juice and enhance the accumulation of specific glucosides that have anticancer effects |
759215 |
2.4.1.210 | metabolism |
enzyme LGT is important in the limonoid metabolism pathway in Citrus plants. Limonoid glucosyltransfease (LGT) is the only single regulatory enzyme that is able to convert all limonoid aglycones such as nomilin, obacunone, and ichangin present in Citrus spp. to their respective glucosides, in addition to limonoate A-ring lactone (LARL) to limonin glucopyranoside. During juicing process bitter limonin is immediately produced from LARL precursor by limonin D-ring lactone hydrolase (LLH) regulatory enzyme, especially in early to mid-stage developed Citrus fruits |
759215 |
2.4.1.210 | metabolism |
limonoid glucosyltransferase (LGT) is a regulatory enzyme in the citrus limonoid biosynthetic pathway. Limonoid biosynthesis in plants, overview |
759285 |
2.4.1.210 | more |
enzyme homology structure modeling |
759676 |
2.4.1.210 | more |
inhibition of the enzyme acxadtivity by Cu2+ and Hg2+ ions suggests that thiol, carboxyl groups or histidine residues are directly or indirectly involved in the catalytic mechanism of the LGT enzyme. Inhibitory efxadfect of citraconic anhydride suggests the lysine or arginine may be involved in catalytic activity of pummelo LGT |
759285 |